Maniac (2018) Maniac follows Annie Landsberg and Owen Milgrim, two strangers drawn to the late stages of a mysterious pharmaceutical trial, each for their own reasons. Annie is disaffected and aimless, fixated on broken relationships with her mother and her sister; Owen, the fifth son of wealthy New York industrialists, has struggled his whole life with a disputed diagnosis of schizophrenia. Neither of their lives have turned out quite right, and the promise of a new, radical kind of pharmaceutical treatment—a sequence of pills its inventor, Dr. James K. Mantleray, claims can repair anything about the mind, be it mental illness or heartbreak—draws them and ten other strangers to the facilities of Neberdine Pharmaceutical and Biotech for a three-day drug trial that will, they’re assured, with no complications or side-effects whatsoever, solve all of their problems, permanently.
Annie Landsberg and Owen Milgrim are two strangers who are drawn to the late stages of a mysterious pharmaceutical trial. Each has a different reason for participating in the experiment -- she is disaffected and aimless, fixated on broken relationships with her mother and sister, while he has struggled throughout his life with a disputed diagnosis of schizophrenia. The radical treatment, using pills that the inventor claims can repair anything about the mind, draws Annie, Owen and 10 other subjects into a three-day drug trial that they're told will permanently solve all of their problems, with no complications or side effects. Unfortunately, things don't go as planned.